01 - Preheat oven to 350°F. Grease a 12-cup muffin tin generously or line with paper liners.
02 - In a medium bowl, toss the diced rhubarb with 1/2 cup granulated sugar and 2 tablespoons melted butter until evenly coated. Spoon approximately 1 to 2 tablespoons of the mixture into the bottom of each muffin cup, pressing lightly to form an even layer.
03 - In a large mixing bowl, whisk together the all-purpose flour, 3/4 cup granulated sugar, baking powder, baking soda, and salt until well combined.
04 - In a separate bowl, beat together the cooled melted butter, eggs, whole milk, and vanilla extract until smooth and homogeneous.
05 - Pour the wet ingredient mixture into the dry ingredients. Fold gently with a rubber spatula until just combined, stopping as soon as no dry streaks remain. Take care not to overmix, as this will produce tough muffins.
06 - Divide the batter evenly among the prepared muffin cups, spooning it directly over the rhubarb layer. Fill each cup approximately three-quarters full.
07 - Bake for 23 to 25 minutes, rotating the tin halfway through, until the muffin tops are golden brown and a toothpick inserted into the center of a muffin comes out clean.
08 - Allow the muffins to cool in the tin for 5 minutes. Run a thin knife around the edges of each muffin, then carefully invert the tin onto a wire rack to release the muffins with the caramelized rhubarb topping facing upward.
09 - Serve warm or at room temperature. These muffins pair beautifully with vanilla ice cream or a dollop of freshly whipped cream if serving as a dessert.